Preventing Cancer from Spreading

Researcher Calvin Roskelley and his team are studying a key mechanism in cancer progression: the ability of circulating cancer cells to cluster together. These clusters increase their chances of surviving in the bloodstream, resisting treatments, and forming new tumors elsewhere in the body.

To counter this process, the team has developed antibodies capable of recognizing a protein present on the surface of cancer cells. By blocking this protein, the researchers hope to prevent the cells from clustering together, reduce their ability to form metastases, and make them more vulnerable to treatments.

The project will evaluate the effectiveness of these antibodies in several types of cancer, including breast, pancreatic, and ovarian cancers. Ultimately, this approach could lead to a new therapeutic strategy aimed at slowing the spread of cancer before metastases are even able to establish themselves.

Thanks to the support of CRS and its donors, researchers can explore new ways to prevent the spread of cancer. Your support contributes to the development of innovative approaches that could limit the occurrence of metastases, improve treatment effectiveness, and offer better outcomes for people affected by the disease.